1. The role of Hippo signaling pathway in physiological cardiac hypertrophy

Majid Gholipour* , Arezoo Tabrizi

Bioimpacts. 2020;10(4): 251-257. doi: 10.34172/bi.2020.32

PMCID: PMC7502907 PMID: 32983941 Scopus ID: 85092016587

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Increased MAP4K1 expression did not influence Lats1 activation. The exercise training protocol suppressed Mst1 and Lats1 (Hippo pathway) and caused an increase in Yap1 expression level, which led to physiological cardiac hypertrophy in healthy rats.

Original Research

2. The effects of concurrent treatment of silymarin and lactulose on memory changes in cirrhotic male rats

Mozhgan Ghobadi Pour , Naser Mirazi* , Hojatollah Alaei, Maryam Radahmadi, Ziba Rajaei, Alireza Monsef Esfahani

Bioimpacts. 2020;10(3): 177-186. doi: 10.34172/bi.2020.22

PMCID: PMC7416014 PMID: 32793440 Scopus ID: 85089309823

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The rat cirrhotic model is made by using thioacetamide hepatotoxin for 18 weeks. The cirrhotic rats treated to some degrees by using lactulose and silymarin known standard drugs for 8 weeks.

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